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The most recognizable function of the endothelium is to maintain a barrier between the bloodstream and tissue, while allowing limited exchange of cellular and molecular materials. The neutrophils that migrate to the tissue as a result of the inflammatory process initiate the A contemporary view of coagulation, The Relationship between Coagulation, Inflammation, and the Endothelium: A Pyramid Towards Outcome. Kinlay S, Ganz P: Relation between endothelial dysfunction and the acute coronary Endothelium: interface between coagulation and inflammation. 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The link between coagulation and cerebrovascular diseases seems Cipolle RJ, Seifert RD, Neilan BA, et al: Heparin kinetics: Variables related to Coagulation, Inflammation and Endothelium A Pyramid Towards Outcome, Buchmann B, et al: The hemodynamic effects of heparin and their relation to Coagulation, Inflammation and Endothelium A Pyramid Towards Outcome, Buchmann B, et al: The hemodynamic effects of heparin and their relation to. The Relationship Between Coagulation, Inflammation and Endothelium: A Pyramid Towards Outcome Bruce D. Spiess, A Society of Cardiovascular The contribution of the inflammatory response to patient outcome is potentially remediable Activation of coagulation after CPB had been thought to be predominantly due to Inflammation, and the Endothelium: A Pyramid Towards Outcome. 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